Natural History

RZHRG continues to follow a cohort of 85 long-term survivors--all women--in Kigali, Rwanda. Many of these women first tested HIV positive in 1986, survived the 1994 genocide, and are alive and well in 2005. There is great scientific interest in why these women remain healthy despite being HIV infected for nearly 25 years. Approximately 45 women are on antiretrovirals.

RZHRG - Natural History

This unique group of women provides an excellent opportunity to further analyze host and receiver genetics related to the progression of the HIV virus.

Survival Probability: Rwandan women with HIV have survived over 25 years with the infection, a cohort continually studied by RZHRG


• Approximately 25 million Africans are HIV+ and 225 million adults are HIV- and married, at risk of acquiring HIV within their marriages.

•The U.S. government spends $2.2 billion annually – 10 percent of the entire U.S. bilateral foreign aid budget -- to provide antiretroviral therapy to 3 million Africans.

•Treating one ART patient over the course of 10 years costs about $7000.

•The World Health Organization (WHO) estimates that five new people are infected by HIV for every two who receive antiretroviral therapy (ART).

RZHRG - Natural History